
What happens when a child outgrows his trusty Imaginary Friend, the pal that stuck with him through all of the highs and lows of growing up? Well, these creations pack up and head for Foster's Home for Imaginary Friends! Foster's is a one-of-a-kind Victorian mansion filled with hundreds of unique characters from all over the world, thought up by completely different children for completely different reasons. These creatures all live together in this vast, sprawling home with more rooms than you could ever dream possible! Mac, a clever but somewhat shy 8-year-old boy, discovers Foster's when his mom tells him he's too old for his Imaginary Friend Blooregard. Not ready to part with his trouble making best buddy, Mac takes Bloo to Foster's with the hope of giving him a safe place to live, while still being able to visit every day.
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Eduardo runs away from the Home to prove his bravery, but ends up over his head in a fight.

Bloo gets a nasty case of the hiccups and must get rid of them before the big Imaginary Friend Pageant.

A camping trip becomes a problem when Bloo eats all the food.

The Duchess is adopted by Mac's neighbors, and the Foster's don't want to take her back.

A suspicious imaginary friend shows up at the house, and Frankie is out to prove him a fraud.

Mac and the crew win a trip to Europe.

The house is filling up with imaginary friends, thanks to a girl named Goo.

Mr. Herriman tries to conceal his carrot addiction, which causes a lot of trouble at Foster's.

Although Eduardo is infested with fleas, he soon befriends them, but Frankie and Mr. Herriman want to get rid of them.

Mac and Bloo collaborate on a movie, which turns into a hit. Later, they must make an even better sequel for a film contest.

Frankie faces a tough campaign against Mr. Herriman as they both compete to be president of Foster's.

A single room opens up in the house, prompting Eduardo, Bloo and Coco to compete for it.

Everyone becomes obsessed with card collection when Coco lays magical eggs filled with cards.

Mac starts to doubt Santa's existence when a hoard of imaginary Santas appear. Bloo sets out to prove that he's real.